MUSCLE PAIN AND PHYSICAL RECOVERY AFTER CONVULSIVE SEIZURES

Why can the body hurt after a convulsive seizure?

After a tonic–clonic or other strongly convulsive seizure, somebody may wake with:

  • aching muscles

  • stiffness

  • back pain

  • neck discomfort

  • sore shoulders

  • bruising

  • tongue or cheek pain

  • headache

  • weakness

  • or a general feeling that their entire body has been physically strained.

Muscle soreness after a tonic–clonic seizure is a recognised part of recovery. During the seizure, the tonic phase produces powerful sustained muscle stiffening, followed by repeated rhythmic contraction and relaxation during the clonic phase.

But pain after a seizure should not automatically be dismissed as:

“just sore muscles.”

Convulsive seizures can also cause:

  • soft-tissue injuries

  • fractures

  • joint dislocations

  • spinal injuries

  • oral injuries

  • and, rarely, substantial muscle breakdown known as rhabdomyolysis.

The challenge is knowing which pain fits ordinary physical recovery and which pain needs further investigation.

The muscles work extremely hard during a tonic–clonic seizure

A tonic–clonic seizure has two major motor phases.

During the tonic phase, muscles become strongly contracted and the body may become rigid.

During the clonic phase, muscles repeatedly contract and relax, producing rhythmic jerking.

These involuntary contractions can involve:

  • the arms

  • legs

  • trunk

  • neck

  • jaw

  • and respiratory muscles.

Afterwards, muscles may feel:

  • tender

  • heavy

  • stiff

  • weak

  • or painful with movement.

This is one reason a seizure lasting only a few minutes can produce physical after-effects lasting much longer.

Muscle soreness is different from postictal exhaustion

Someone may describe both as:

“I feel completely wiped out.”

But they are not exactly the same phenomenon.

Postictal exhaustion can involve:

  • profound tiredness

  • sleepiness

  • cognitive slowing

  • and the need to sleep.

Post-seizure muscle pain involves physical discomfort arising from:

  • intense contractions

  • soft-tissue strain

  • bruising

  • or injury.

The two commonly occur together.

Related Information Hub page:
Postictal Exhaustion and Sleep

Muscle soreness is also different from Todd's paresis

Todd's paresis is a temporary focal neurological weakness after a seizure.

Muscle soreness is different.

For example:

Both thighs aching when walking after a tonic–clonic seizure

is more consistent with general muscular recovery.

By contrast:

the right arm and right leg suddenly having markedly reduced strength

may represent Todd's paresis or another focal neurological problem.

Pain, tiredness and neurological weakness can coexist, which is why the exact symptom matters.

Related Information Hub page:
Todd's Paresis — Temporary Weakness After a Seizure

How long can ordinary muscle soreness last?

There is no universal recovery time.

Some people feel relatively normal within hours.

Others may remain:

  • sore

  • stiff

  • bruised

  • or physically depleted

into the following day or longer.

The postictal state itself can last from minutes to days depending on the symptom and individual. Research emphasises that post-seizure recovery is highly variable rather than governed by one fixed timetable.

Muscle pain should generally trend towards improvement.

Pain that is:

  • severe

  • localised

  • worsening

  • preventing use of a limb

  • or persisting unexpectedly

deserves closer assessment.

Not all post-seizure pain comes from the muscle contractions

Some pain comes from trauma during the seizure.

A person may:

  • fall

  • strike furniture

  • hit the floor

  • twist a limb

  • land on a shoulder

  • injure the head

  • bite the tongue

  • or sustain another injury.

Studies of epilepsy-related injuries describe:

  • lacerations

  • bruises

  • fractures

  • burns

  • concussion

  • dental injuries

  • and joint dislocations.

So:

“Everything hurts after my seizure”

may represent a combination of muscle contraction and physical injury.

A person may not remember being injured

Seizures that impair consciousness or memory can make injury assessment more difficult.

The person may have:

  • no memory of falling

  • no memory of hitting an object

  • incomplete memory of the recovery period

  • or no idea which body part struck the ground.

Pain discovered later may therefore be the first indication that an injury occurred.

Related Information Hub page:
Missing Time and Memory Gaps Around Seizures

Bruising and soft-tissue injuries are common seizure injuries

Minor injuries such as:

  • bruises

  • abrasions

  • cuts

  • and soft-tissue pain

occur more commonly than major fractures.

In one epilepsy-clinic study, 14% of participants reported epilepsy-related injury or accidents during a three-month period. Lacerations, bruises and abrasions were among the commonest injuries, while fractures and burns were less frequent.

That particular figure comes from one clinical population and should not be treated as a universal rate.

Risk varies substantially according to:

  • seizure type

  • seizure frequency

  • falls

  • environment

  • and severity of epilepsy.

Shoulder pain deserves particular attention

Seizures have an unusual relationship with shoulder injuries.

Powerful muscle contractions can occasionally dislocate the shoulder even without a dramatic external impact.

Posterior shoulder dislocation is particularly associated with convulsive seizures.

A systematic review of posterior shoulder dislocations found seizures implicated in around 38% of the patients included.

Another seizure-specific series found posterior dislocations in 12 of 15 people who sustained seizure-related shoulder dislocations.

This does not mean shoulder dislocation is common after seizures.

Posterior dislocation itself is rare.

But severe shoulder pain after a convulsion deserves attention because the injury can be missed.

Shoulder dislocations can be accompanied by fractures

Seizure-related shoulder injuries may be complex.

A systematic review of posterior shoulder dislocations found associated injuries in around 65% of affected shoulders, including fractures, bone defects and rotator-cuff injuries.

A separate review of upper-limb orthopaedic injuries in people with epilepsy also found frequent associated fractures among published severe cases.

Warning signs include:

  • severe shoulder pain

  • inability to move the arm normally

  • obvious deformity

  • unusual positioning of the arm

  • swelling

  • or significant pain when attempting movement.

A suspected dislocation should not be forcibly manipulated by an untrained person.

Back pain should not automatically be dismissed as muscular

Back soreness can certainly result from forceful muscle contractions.

However, seizures can rarely cause vertebral fractures, even without a fall.

A 2024 systematic review found postictal vertebral fractures were rare but potentially serious. The proposed mechanism involves violent muscle contractions placing substantial forces through the spine.

Another systematic review found seizure-induced spinal fractures most commonly involved the thoracic and lumbar spine. Persistent back pain after a seizure — particularly when associated with neurological symptoms — warranted investigation.

A fracture can occur from the convulsion itself

People often assume a fracture requires:

fall → impact → broken bone.

That is not always the case during a powerful convulsive seizure.

Muscle contractions themselves can generate enough force to cause some fractures.

A systematic review of fractures related to convulsive seizures found commonly reported injuries included:

  • posterior shoulder fracture-dislocations

  • thoracic and lumbar vertebral compression fractures

  • skull and jaw fractures

  • and femoral-neck fractures.

The evidence base consisted largely of retrospective reports and case series, so these proportions describe the published fracture cases, not the risk faced by every person having a seizure.

Severe localised pain is different from general aching

Ordinary post-convulsive soreness often feels relatively diffuse.

For example:

  • both thighs ache

  • the shoulders and back feel stiff

  • the body feels as if it has done intense exercise.

An injury may be more likely when there is:

  • one very painful point

  • swelling

  • deformity

  • inability to bear weight

  • inability to use a limb

  • severe pain with movement

  • significant tenderness directly over a bone

  • or pain that becomes progressively worse.

There are no perfect rules, but the pattern of pain matters.

Persistent severe back pain needs assessment

A spinal fracture may initially be mistaken for ordinary muscle pain because back soreness is expected after a convulsion.

The systematic review of seizure-induced spinal fractures specifically recommends considering spinal injury when somebody has persistent thoracic or lower-back pain following a seizure, particularly when neurological deficits are present.

New:

  • leg weakness

  • numbness

  • difficulty walking

  • bladder or bowel dysfunction

  • or altered sensation

alongside severe back pain requires urgent medical assessment.

Head and neck pain need their own assessment

A person who collapsed during a seizure may have injured:

  • the scalp

  • skull

  • brain

  • face

  • or neck.

Headache may be postictal.

Neck discomfort may be muscular.

But pain may also reflect trauma.

NICE head-injury guidance identifies features such as:

  • persistent headache

  • vomiting

  • altered consciousness

  • amnesia

  • neurological deficits

  • and seizures following a head injury

as reasons for further medical assessment.

Related Information Hub pages:

Postictal Headache

Seizure Injuries and Head Injuries

Tongue and mouth pain are common physical consequences

During a convulsive seizure, somebody may bite:

  • the tongue

  • inside of the cheek

  • lip

  • or other oral tissues.

This can produce:

  • swelling

  • soreness

  • bleeding

  • difficulty eating

  • or pain when speaking.

Research shows that lateral tongue injury can provide useful diagnostic information in the assessment of a transient loss-of-consciousness event, although tongue biting itself is not present in most epileptic seizures.

A 2026 report also highlights that seizure-related tongue wounds can occasionally be substantial enough to need specialist oral or surgical care.

Never put an object in somebody's mouth during a seizure

Tongue injuries do not justify attempting to:

  • hold the tongue

  • insert a spoon

  • place fingers in the mouth

  • use a bite block

  • or force another object between the teeth.

A person cannot “swallow their tongue”.

A medical review of this persistent first-aid myth highlights the harm that can result from putting objects in the mouth during a seizure.

Seizure first aid centres on protecting the person from external injury — not forcing the mouth open.

Dental injuries can also occur

Teeth may be:

  • chipped

  • fractured

  • loosened

  • displaced

  • or knocked out

during seizures.

A systematic review and meta-analysis found that oral and maxillofacial injuries are an important part of epilepsy-related trauma, including:

  • soft-tissue injury

  • dental trauma

  • and facial fractures.

Dental pain or a visibly damaged tooth should therefore not simply be considered part of normal postictal soreness.

What is creatine kinase?

Creatine kinase — CK — is an enzyme found predominantly in muscle and other tissues.

When skeletal muscle cells are damaged, CK can leak into the bloodstream.

Blood CK can therefore rise after:

  • muscle trauma

  • strenuous exercise

  • prolonged immobility

  • seizures

  • certain medicines

  • metabolic disorders

  • and many other causes.

A raised CK level indicates muscle-cell injury but does not, by itself, explain the cause or establish how serious the clinical situation is.

CK can rise after tonic–clonic seizures

Convulsive seizures can produce measurable skeletal-muscle injury.

In one hospital study of people assessed after generalised tonic–clonic seizures, CK was elevated in approximately 59% of those studied.

Most rises were relatively modest.

Very large CK increases consistent with severe muscle injury were much less common.

These figures came from a selected emergency/hospital population and should not be applied directly to every seizure occurring in the community.

A raised CK is not the same as rhabdomyolysis

This distinction is important.

Small or moderate CK rises can follow intense muscle activity.

Rhabdomyolysis refers to substantial skeletal-muscle breakdown with release of intracellular muscle contents into the circulation.

Definitions used in research vary considerably, although markedly raised CK is usually part of the diagnosis. A systematic review found substantial inconsistency in the exact CK threshold used to define rhabdomyolysis.

So:

CK raised after seizure

does not automatically mean:

rhabdomyolysis.

What is rhabdomyolysis?

Rhabdomyolysis occurs when damaged skeletal muscle releases substances including:

  • creatine kinase

  • myoglobin

  • potassium

  • phosphate

  • and other intracellular components.

Seizures are one recognised cause.

In severe cases, these biochemical changes can contribute to:

  • acute kidney injury

  • dangerous electrolyte disturbances

  • abnormal heart rhythms

  • or other systemic complications.

Fortunately, severe seizure-associated rhabdomyolysis is much less common than ordinary muscle soreness.

What might rhabdomyolysis feel like?

Possible symptoms include:

  • severe or increasing muscle pain

  • pronounced muscle tenderness

  • swelling

  • marked weakness

  • reduced urine output

  • or unusually dark urine.

However, the traditional combination of:

muscle pain + weakness + dark urine

is actually present in only a minority of people with rhabdomyolysis.

Its absence therefore does not completely exclude the condition.

Dark urine can be an important warning sign

Myoglobin released from damaged muscle can cause urine to appear:

  • dark brown

  • red-brown

  • or tea/cola coloured.

Dark urine after a severe or prolonged convulsive event should not simply be assumed to represent:

  • dehydration

  • incontinence

  • or concentrated urine.

It may require medical assessment and blood/urine testing.

Blood in urine has other possible causes too.

Severe rhabdomyolysis can affect the kidneys

Myoglobin and other consequences of widespread muscle injury can contribute to acute kidney injury.

A 2026 case report describes severe seizure-associated rhabdomyolysis with CK rising above 89,000 IU/L and stage-three acute kidney injury following a generalised seizure.

Individual case reports demonstrate what can happen, not how often it happens.

In the larger hospital study mentioned earlier, severe rhabdomyolysis was identified in only a small proportion of generalised tonic–clonic seizure presentations.

Prolonged or repeated convulsions increase concern

Muscle injury becomes more plausible when convulsive activity is:

  • prolonged

  • repeated

  • or part of convulsive status epilepticus.

Repeated intense muscle contractions expose the muscles to substantially more physiological stress than a brief seizure.

This is another reason prolonged convulsive seizures require emergency treatment.

Related Information Hub pages:

Status Epilepticus — When a Seizure Becomes a Medical Emergency

Seizure Clusters and Rescue Medication

Rhabdomyolysis is diagnosed medically

It cannot be reliably identified simply from how sore somebody feels.

Assessment may include:

  • CK

  • kidney function

  • electrolytes

  • urine testing

  • hydration status

  • and other investigations depending on the clinical situation.

A 2023 seizure-related case series and literature review emphasised serial CK, kidney-function and electrolyte assessment where substantial seizure-associated muscle injury is suspected.

Routine CK testing is not necessarily required after every uncomplicated seizure.

The clinical context matters.

Severe muscle pain after every seizure deserves discussion

Repeated substantial muscular pain may affect:

  • mobility

  • sleep

  • independence

  • work

  • exercise

  • and overall quality of life.

It may also provide useful information about:

  • seizure severity

  • convulsive duration

  • clustering

  • falls

  • and injury burden.

The physical recovery period should therefore be considered part of the seizure's overall impact rather than ignored because the visible convulsions have stopped.

The seizure can be brief while recovery is prolonged

For example:

convulsion: 90 seconds

muscle soreness: 24 hours

bruising: several days

shoulder injury: weeks or longer.

Seizure duration alone therefore substantially underestimates the total physical burden of some events.

Should someone exercise immediately afterwards?

There is no universal rule.

Someone who remains:

  • confused

  • dizzy

  • weak

  • exhausted

  • or significantly sore

should not be pressured into physical activity simply to prove that they have recovered.

Early recovery should prioritise:

  • safety

  • rest

  • recognising injuries

  • and returning to usual activity as the person's condition allows.

Severe or focal pain should be assessed before assuming exercise is appropriate.

Gentle movement may be reasonable once recovery is established

Once the person is:

  • fully alert

  • neurologically back towards baseline

  • not seriously injured

  • and able to move safely,

gentle normal movement may help prevent unnecessary stiffness.

But there is no evidence-based requirement to:

“stretch the seizure out”

or force painful muscles through exercise immediately afterwards.

Pain should guide caution, particularly where an injury has not been excluded.

What about pain relief?

Minor aches following an uncomplicated tonic–clonic seizure may sometimes be managed with the person's usual suitable pain-relief strategy. The Epilepsy Foundation notes that common analgesics may help minor post-seizure aches.

But pain medicine is not universally safe.

Suitability depends on factors such as:

  • allergies

  • stomach disease

  • kidney disease

  • pregnancy

  • anticoagulant treatment

  • other medicines

  • and the nature of the injury.

Severe pain should not simply be masked when a fracture, dislocation, head injury or significant muscle injury may be present.

Hydration can be part of ordinary recovery — once swallowing is safe

After the person is fully alert and swallowing normally, returning to ordinary fluid intake may be reasonable unless their medical condition requires fluid restriction.

Fluids should not be forced on somebody who remains significantly drowsy or confused because of choking and aspiration risk.

If rhabdomyolysis is suspected, medical fluid management is different and may require intravenous treatment and monitoring.

It should not be treated simply by telling someone to drink large quantities of water at home.

Physical examination after a seizure can identify injuries

Once immediate seizure first aid is complete, it can be useful to look for:

  • bleeding

  • bruising

  • swelling

  • deformity

  • tenderness

  • reduced movement

  • dental damage

  • tongue injury

  • burns

  • or pain when standing.

The person may initially be too confused or sleepy to report injuries reliably.

A second check after they become more alert can therefore be useful.

Do not assume someone would know if they broke something

Pain perception, memory and awareness may all be altered during the immediate postictal period.

The person may initially:

  • deny pain

  • be unable to localise it

  • walk despite injury

  • or fail to remember the mechanism.

An injury may only become obvious as postictal confusion decreases.

Falls are not the only source of injury

Even when somebody was already:

  • in bed

  • sitting

  • or lying on the floor,

injury is still possible.

Forceful contractions themselves can contribute to:

  • shoulder dislocation

  • spinal fracture

  • muscle injury

  • and oral trauma.

The absence of a witnessed fall therefore does not completely exclude musculoskeletal injury.

Bone health also matters

People with epilepsy may have additional fracture risks unrelated to the force of one seizure.

These can include:

  • repeated falls

  • reduced mobility

  • underlying neurological disability

  • osteoporosis

  • vitamin D deficiency

  • and the effects of some long-term antiseizure treatments on bone metabolism.

Older meta-analysis data show increased fracture risk in people with epilepsy and reduced bone mineral density in some populations.

This is a separate long-term issue from ordinary postictal muscle soreness.

Related Information Hub page:
Bone Health, Vitamin D and Epilepsy Medicines

Burns can also produce pain after seizures

Pain discovered during recovery may occasionally come from:

  • hot liquids

  • ovens

  • cookers

  • fires

  • radiators

  • bath water

  • or another heat source.

A 2026 review of epilepsy-related burns found that burns often occurred during ordinary activities such as cooking or bathing and could sometimes cause severe morbidity.

Burn prevention is therefore an important component of epilepsy safety.

Related Information Hub page:
Cooking, Heat and Fire Safety

When is pain particularly concerning?

Medical assessment should be considered when there is:

  • severe or worsening pain

  • obvious deformity

  • inability to use a limb normally

  • inability to bear weight

  • significant swelling

  • severe shoulder pain

  • persistent severe back or neck pain

  • numbness or new neurological weakness

  • significant head injury

  • substantial bleeding

  • a deep tongue or facial wound

  • dark urine

  • very reduced urine output

  • major muscle swelling

  • or failure to recover normally.

Emergency care may be required depending on the severity and associated symptoms.

Severe pain after a first convulsive seizure deserves careful examination

After a first seizure, attention understandably focuses on:

Why did the seizure happen?

But physical injury can easily be overlooked while neurological investigations are being arranged.

A person presenting after a first convulsive event may simultaneously need assessment for:

  • head injury

  • shoulder dislocation

  • fracture

  • oral injury

  • or severe muscle damage.

Both problems can be present at the same time.

Pain that gets worse rather than better needs reconsideration

Ordinary muscular soreness should generally improve with recovery.

A pattern such as:

mild pain immediately after seizure → increasingly severe pain over several hours

should prompt reconsideration.

Possible explanations include:

  • expanding swelling

  • an overlooked fracture

  • joint injury

  • significant muscle injury

  • or another medical problem.

The fact that the initial examination appeared reassuring does not make later deterioration irrelevant.

A person's usual pattern is useful — but not absolute

Someone may normally experience:

aching thighs + stiff shoulders + sleep → much better next day.

That history can help interpret future episodes.

But if a later seizure produces:

one shoulder completely immobile and extremely painful

it should not be dismissed simply because they “always hurt after seizures”.

Changes from the person's normal recovery pattern matter.

Record injuries as part of the seizure

A seizure diary can record:

  • where the pain occurred

  • whether there was a fall

  • visible bruising

  • tongue or mouth injury

  • ability to move each limb

  • ability to walk

  • how long soreness lasted

  • whether medical treatment was needed

  • and whether an injury was diagnosed.

This provides a more complete picture of seizure burden than simply recording:

“one tonic–clonic seizure.”

Injuries can influence treatment decisions

Repeated seizure-related:

  • fractures

  • burns

  • falls

  • dislocations

  • or serious soft-tissue injuries

can materially affect the risk-benefit discussion around epilepsy treatment.

Seizure severity is not measured only by frequency.

A relatively infrequent seizure that repeatedly causes major injury may still carry substantial clinical significance.

Prevention matters

Not every seizure injury can be prevented.

But risk may sometimes be reduced through:

  • improved seizure control

  • safer bathing and cooking arrangements

  • reducing dangerous fall hazards

  • appropriate workplace adaptations

  • attention to bone health

  • seizure action plans

  • and individualised environmental changes.

Prevention should be proportionate.

The aim is to reduce avoidable harm without unnecessarily removing independence.

The most important message

Muscle pain after a convulsive seizure is real and medically understandable.

During tonic–clonic seizures, muscles undergo powerful involuntary stiffening and repeated contractions. Soreness, stiffness and general physical aching can therefore form part of ordinary recovery.

But pain after a seizure has more than one possible cause.

It may represent:

  • muscular soreness

  • bruising

  • soft-tissue injury

  • a fall

  • joint dislocation

  • fracture

  • spinal injury

  • oral injury

  • or, rarely, severe skeletal-muscle breakdown.

Shoulder and spinal injuries deserve particular attention because seizures can occasionally generate enough muscular force to cause significant injury even without a fall.

Blood CK often rises to some degree after generalised tonic–clonic seizures in hospital populations, but severe rhabdomyolysis is much less common.

Possible warning signs of substantial muscle injury include:

  • severe or increasing muscle pain

  • major swelling

  • pronounced weakness

  • dark urine

  • or reduced urine output.

The important distinction is therefore:

general soreness that gradually improves

versus:

focal, severe, worsening or otherwise unusual pain.

The seizure may have lasted minutes.

The body's physical recovery — and any injuries caused by the event — can last much longer.

Related Information Hub pages

After the Seizure — Understanding the Postictal State

Postictal Exhaustion and Sleep

Todd's Paresis — Temporary Weakness After a Seizure

Postictal Headache

Seizure Injuries and Head Injuries

Seizure First Aid

Status Epilepticus — When a Seizure Becomes a Medical Emergency

Bone Health, Vitamin D and Epilepsy Medicines

Cooking, Heat and Fire Safety

When Recovery Is Taking Too Long

Sources and further reading

Pottkämper JCM and colleagues — The postictal state: What do we know? — Epilepsia, 2020
Comprehensive review of the postictal state, its highly variable duration and the range of neurological and physical effects following seizures.

Laboratory markers of cardiac and metabolic complications after generalized tonic-clonic seizures
Hospital study demonstrating that CK elevation is common after generalised tonic–clonic seizures while severe rhabdomyolysis is considerably less frequent.

Manrique-Guzman and colleagues — Postictal vertebral fractures: incidence, risk factors, and clinical outcomes — Systematic review, 2024
Recent systematic review documenting rare vertebral fractures caused by violent seizure-related muscle contraction and emphasising the importance of recognising persistent postictal spinal pain.

Robles and Guerrero-Maldonado — Seizure-Induced Spinal Fractures: A Systematic Review, 2022
Review showing that seizure-induced spinal fractures predominantly involve the thoracic and lumbar spine and should be considered when significant back pain or neurological deficits follow convulsions.

Grzonka and colleagues — Bone fractures from generalized convulsive seizures and status epilepticus: A systematic review, 2019
Review of reported seizure-associated fractures, including posterior shoulder fracture-dislocations and vertebral compression fractures, and the difficulty of recognising fractures during postictal recovery.

Incidence of associated injury in posterior shoulder dislocation: systematic review
Systematic review demonstrating the strong association between posterior shoulder dislocation, seizures and accompanying fractures or soft-tissue injuries.

Yen and colleagues — A Systematic Review of the Management of Upper Extremity Orthopaedic Injuries in Epileptic Patients, 2022
Review of significant upper-extremity injuries associated with seizures, particularly posterior shoulder dislocation and fracture.

Zutt and colleagues — Rhabdomyolysis: review of the literature
Detailed review of rhabdomyolysis, including seizures among recognised causes, clinical manifestations and potential renal complications.

Tongue biting in epileptic seizures and psychogenic events: an evidence-based perspective
Systematic review examining tongue injury as a clinical feature of convulsive seizures and distinguishing the value of lateral tongue injury from non-specific tongue biting.

NICE NG232 — Head injury: assessment and early management
UK-specific guidance covering neurological, behavioural, vomiting and other warning signs requiring assessment after head trauma.

Information reviewed: September 2026.

This page provides general educational information for an international audience. Pain after a seizure can arise from ordinary muscle contraction or from significant injury. Severe, focal, worsening or persistent pain, deformity, inability to use a limb, significant spinal or head pain, new neurological symptoms, dark urine or reduced urine output require appropriate medical assessment. Emergency and healthcare pathways vary between countries.

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